Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Computer-aided identification, synthesis, and biological evaluation of DNA polymerase η inhibitors for the treatment of cancer - ScienceDirect
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ | PLOS ONE
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Inhibition of host NF-kappa-B by virus ~ ViralZone
Mechanism of Replicative DNA Polymerase Delta Pausing and a Potential Role for DNA Polymerase Kappa in Common Fragile Site Replication - ScienceDirect
IJMS | Free Full-Text | Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress
Crystal Structure of the Catalytic Core of Human DNA Polymerase Kappa: Structure
Journal of Cellular Physiology | Cell Biology Journal | Wiley Online Library
Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA | Nature Communications
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Unravelling roles of error-prone DNA polymerases in shaping cancer genomes | Oncogene
Frontiers | Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH)
Translesion DNA Synthesis in Cancer: Molecular Mechanisms and Therapeutic Opportunities | Chemical Research in Toxicology
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites | PNAS
Journal of Cellular Physiology | Cell Biology Journal | Wiley Online Library
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide - ScienceDirect
Structure of human Y-family polymerase kappa. (A) Cartoon diagram... | Download Scientific Diagram
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis - ScienceDirect
DNA polymerase kappa Inhibitors (IC50, Ki) | AAT Bioquest
Genes | Free Full-Text | Maintenance of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases
Anti-DNA polymerase kappa POLK Antibody
